George Little may refer to:
Politics and government George E. Little, Pentagon/Department of Defense press secretary George Little (Manitoba politician) (died 1940), Manitoba MLA George Little (naval officer) (1754–1809), American naval officer during the Revolutionary War George Little (New Brunswick politician) (1937–2021), leader of the New Democratic Party of New Brunswick George Little (North Carolina politician) (1942–2024), Republican politician from North Carolina George W. Little, New York politician
Sports George Little (American football coach) (1889–1957), American football and basketball coach, 1914–1926 George Little (defensive lineman) (born 1963), American football player George Little (footballer) (1915–2002), English professional footballer Dan McLeod (wrestler) (1860–1958), Scottish wrestler, born George Little
Entertainment George L. Little (c. 1950–2014), American costume designer George Little (actor) (1928–2022), English television actor, father of Tasmin Little