Blotto may refer to:
Blotto (biology), a reagent used in immunological assays Blotto, a colloquial term meaning drunkenness Blotto (film), a 1930 Laurel and Hardy short comedy film Blotto (band), an Albany, NY, rock band in the late 1970s and early 1980s Blotto (restaurant), Seattle, Washington, U.S. Blotto games, a class of zero-sum games named after a fictional Colonel Blotto