MacNicol is a surname. It is a patronymic form of the personal name Nicol, which is a form of Nicholas. For the etymology of the surname McNicol this web page cites: Dictionary of American Family Names, Oxford University Press, . It comes from both German and Celtic origins.

Notable people with the surname include:

Bessie MacNicol (1869–1904), Scottish painter Donald MacNicol (1735–1802), Scottish clergyman John Ritchie MacNicol (1878–1950), Canadian politician Quinn MacNicol (born 2008), Australian soccer player Peter MacNicol (born 1954), American actor

See also MacNicol (crater), crater on Mercury Clan MacNeacail, sometimes known as Clan MacNicol, Scottish clan long associated with the Isle of Skye

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