Cardinale is a surname. Notable people with the surname include:
Claudia Cardinale (1938–2025), Tunisian-born Italian actress Gerald Cardinale (1934–2021), American politician Gerry Cardinale (born 1967), American businessman and investor Igino Eugenio Cardinale (1916–1983), Italian Roman Catholic archbishop and diplomat Lindsey Cardinale (born 1985), American singer Marco Cardinale (born 1973), Italian sports scientist and administrator Salvatore Cardinale (born 1948), Italian politician Tina Cardinale-Beauchemin (born 1966), American athlete
See also Cardenal Cardinal (disambiguation) Cardinali (disambiguation)