Francis Osborne (1593–1659) was an English essayist.
Francis Osborne may also refer to: Francis Osborne, 5th Duke of Leeds (1751–1799), British politician Francis Osborne, 1st Baron Godolphin (1777–1850), British politician Francis D'Arcy-Osborne, 7th Duke of Leeds (1798–1859), British politician Francis D'Arcy Osborne, 12th Duke of Leeds (1884–1964), British diplomat Frank I. Osborne (Francis Irwin Osborne, 1853–1920), Attorney General of North Carolina, 1893–1896
See also Francis C. Osborn Sr., businessman and teacher Frank Osborne (disambiguation) Frances Osborne (born 1969), British author