George Jeffreys may refer to:
George Jeffreys (composer) (c. 1610–1685), composer and organist to Charles I George Jeffreys, 1st Baron Jeffreys (1645–1689), British politician & jurist George Jeffreys, 1st Baron Jeffreys (British Army officer) (1878–1960), British soldier & politician George Jeffreys (pastor) (1889–1962), British religious leader
See also George Jefferies, photographer George Jeffery (disambiguation), several people