You Only Live Once may refer to:
Film You Only Live Once (1937 film), an American crime drama film You Only Live Once (1952 film), a German comedy film You Only Live Once (2017 film), an Argentine action film Zindagi Na Milegi Dobara, or You Only Live Once, a 2011 Indian Hindi-language buddy road comedy-drama film Music Man lebt nur einmal! (You Only Live Once!), a waltz by Johann Strauss II "You Only Live Once" (song), by The Strokes, 2006 "You Only Live Once", a song by Suicide Silence from their 2011 album The Black Crown "You Only Live Once", a song by Unsolved Mysteries from the album Tragic Trouble
Other You Only Live Once (book), a 2016 book written by Jason Vitug You Only Live Once (video game), a 2010 Flash game by Marcus Richter
See also YOLO (aphorism), an acronym for you only live once Yolo (disambiguation) You Only Live Twice (disambiguation)