Coble is a surname. Notable people with the surname include:
Anna Coble, American biophysicist Arthur Byron Coble (1878–1966), American mathematician Bob Coble (born 1953), former mayor of Columbia, South Carolina, USA Dave Coble (1912–1971), American baseball player Drew Coble (born 1947), American baseball umpire Eric Coble, playwright and screenwriter Robert L. Coble (1928–1992), American materials scientist, known for Coble creep Howard Coble (1931–2015), U.S. Representative from North Carolina Paul Coble (born 1953), North Carolina politician, former mayor of Raleigh