Hersleb is a surname. Notable people with the surname include:

Christian Hersleb Horneman (1781–1860), Norwegian jurist and politician Hersleb Vogt (1912–1999), Norwegian diplomat Jacob Hersleb Darre (1757–1841), Norwegian vicar Peder Christian Hersleb Kjerschow (1786–1866), Norwegian clergyman Peder Hersleb (1689–1757), Norwegian-Danish bishop Peter Hersleb Classen (1738–1825), Norwegian-Danish statesman Peter Hersleb Graah Birkeland (1807–1896), Norwegian bishop Peter Hersleb Harboe Castberg (1794–1858), Norwegian priest and politician Svend Borchmann Hersleb (1784–1836), Norwegian professor of theology who also served one term in the Norwegian Parliament Svend Borchmann Hersleb Vogt (1852–1923), Norwegian jurist and politician for the Conservative Party