Play Ball may refer to:
Film and television Playball (film), a 2008 film directed by Alfonso Rodríguez Play Ball (serial), 1925 film by Spencer Gordon Bennet believed to be lost "Play Ball!", an episode in the fourth season of the children's television show Barney & Friends "Play Ball" (Most Dangerous Game), a 2023 television episode "Play Ball" (Quantum Leap), a 1991 television episode Play Ball (film), a 1937 short film Play Ball (1933 film), a Willie Whopper cartoon
Literature and publishing Play Ball (manga), Akio Chiba's 1970s manga, later adapted to anime form Play Ball: Stories of the Ball Field, King Kelly's 1888 autobiography
Theatre Play Ball, an alternative name for play Chicago
Music "Play Ball" (song), a 2014 song by AC/DC "Play Ball" (), a 2002 song by from the album Deep River
See also Ball Play (disambiguation)