Mishin (; masculine) or Mishina (; feminine) is a Russian surname that is derived from Misha, a diminutive for the male given name Mikhail, and literally means Misha's. Mishina is also an unrelated Japanese surname. Notable people with the surname include:

Mishin Alexei Mishin (born 1941), figure skater and coach Alexei Mishin (wrestler) (born 1979) Andrey Mishin (born 1979), boxer Dmitry Mishin (1919–1998), physicist Sergey Mishin (1958–2025), weightlifter Vasily Mishin (1917–2001), engineer Vladimir Mishin (1888–1942), footballer

Mishina Anastasia Mishina, Russian pair skater Daria Mishina, Russian ice hockey player Irina Mishina, Russian journalist and television presenter Larisa Mishina, Russian ice hockey player Masumi Mishina, Japanese softball player Shōei Mishina, Japanese historian Tatiana Mishina, Soviet figure skater Yuji Mishina, Japanese molecular biologist

Fictional characters Eikichi Mishina, character in the video game Persona 2