Frank House, Franks House, or Franke House may refer to:

People Frank House (baseball) (1930–2005), American Major League player Frank House (footballer) (1884–1963), Australian rules footballer

Places Netherlands Anne Frank House, museum dedicated to Anne Frank

United States Alan I W Frank House, Pittsburgh, Pennsylvania, historic Gropius-Breuer masterwork Anderson–Frank House, historic home in Tampa, Florida, listed on the NRHP in Florida George W. Frank House, historic mansion in Kearney, Nebraska John Frank House, in Sapulpa, Oklahoma M. Lloyd Frank Estate, in Portland, Oregon Frank House (Maryville, Missouri), listed on the NRHP in Missouri Charles Frank House and Store, Valley City, OH, listed on the NRHP in Ohio Joseph M. Frank House, Little Rock, AR, listed on the NRHP in Arkansas Charles Franks House, Lanark, IL, listed on the NRHP in Illinois C. F. Franke House, Mason City, IA, listed on the NRHP in Iowa Henry Frank House, Middletown, KY, listed on the NRHP in Kentucky Henry Franks House, Allegan, MI, listed on the NRHP in Michigan Case Study House #25, Long Beach, California

UK Franks House, East London, part of the British Museum, used for the storage and study of their Early Prehistory collections