St. Joe or Saint Joe may refer to:

Communities In the United States: St. Joe, Arkansas Port St. Joe, Florida Saint Joe, Idaho St. Joe, Illinois Saint Joe, Indiana St. Joseph, Michigan, colloquially known as St. Joe St. Joe, Missouri Saint Joe, West Virginia St. Joe, Wisconsin St. Joe, Oregon

Parks and geographic features St. Joe River, in northern Idaho St. Joe National Forest, in the Idaho panhandle St. Joe State Park, in Missouri

Other St. Joe Company, a land developer

See also Saint Joseph (disambiguation) Saint Joseph's (disambiguation)