Mayo House may refer to:
Mayo House (Marvell, Arkansas), listed on the U.S. National Register of Historic Places Helton-Mayo Farm, Bedford, Indiana, listed on the NRHP in Lawrence County, Indiana Mayo Mansion, also known as John C.C. Mayo Mansion and Office, Paintsville, Kentucky, listed on the NRHP in Johnson County, Kentucky Mayo Mansion (Ashland, Kentucky), listed on the NRHP in Boyd County, Kentucky as part of the Bath Avenue Historic District Thomas Mayo House, Paintsville, Kentucky, listed on the NRHP in Johnson County, Kentucky Moore-Mayo House, Bass Harbor, Maine, listed on the NRHP in Hancock County, Maine Mayo House (Portland, Oregon) Dr. William J. Mayo House, Rochester, Minnesota, NRHP-listed Dr. William W. Mayo House, Le Sueur, Minnesota, NRHP-listed Taylor-Mayo House, Richmond, Virginia, listed on the NRHP in Richmond, Virginia
See also Mayo Building (disambiguation) Mayo Hotel, Tulsa, Oklahoma, NRHP-listed