Clarksville Historic District may refer to:
Clarksville Historic District (Clarksville, Missouri), listed on the NRHP in Missouri Clarksville Historic District (Austin, Texas), listed on the NRHP in Texas Clarksville Historic District (Clarksville, Virginia), listed on the NRHP in Virginia
See also Clarksville (disambiguation) Clarksville Architectural District, Clarksville, Tennessee, a historic district listed on the NRHP in Montgomery County, Tennessee Clarksville Industrial District, Clarksville, Tennessee, a historic district listed on the NRHP in Montgomery County, Tennessee