Twice Upon a Time may refer to:
Film and television Twice Upon a Time (1953 film), a British comedy film Twice Upon a Time (1983 film), an American animated film Twice Upon a Time (1998 film), an American fantasy/romantic comedy TV film "Twice Upon a Time" (Doctor Who), a 2017 episode of Doctor Who Il était une seconde fois, a French TV series released in English as Twice Upon a Time Twice Upon a Time..., 1979 Canadian short film
Music Twice Upon a Time (Joe Diffie album) Twice Upon a Time (The Kingston Trio album) Twice Upon a Time – The Singles, a compilation album by Siouxsie and the Banshees
Other uses Twice Upon a Time (book series), a children's fantasy novel series by Wendy Mass