Varilla may refer to:
Varilla (plant), a genus of plants in the family Asteraceae Varilla, Kentucky
People with the name Varilla Appuleia Varilla (fl. 17) the only daughter of Sextus Appuleius and Quinctilla, the sister of Publius Quinctillius Varus Hay–Bunau-Varilla Treaty, signed on November 18, 1903, two weeks after Panama's independence from Colombia Maurice Bunau-Varilla (1856–1944), French press magnate, proprietor of the newspaper Le Matin Philippe-Jean Bunau-Varilla (1859–1940), French engineer and soldier
See also Varillas, a surname