Polypoid melanoma is a rare cutaneous condition, a virulent variant of nodular melanoma. Polypoid melanoma is a subtype of nodular melanoma, the most aggressive form of melanoma (a skin cancer).

Signs and symptoms Polypoid melanoma is distinguished by a profile that resembles cauliflower and an uneven surface.

Treatment Therapies for metastatic melanoma include the biological immunotherapy agents ipilimumab, pembrolizumab, and nivolumab; BRAF inhibitors, such as vemurafenib and dabrafenib; and an MEK inhibitor trametinib.

See also Melanoma List of cutaneous conditions

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