Cotton Exchange Building may refer to:
in the United Kingdom Liverpool Cotton Exchange Building, England Manchester Royal Exchange the United Kingdom's principal cotton exchange from 1729 until 1968 Blackburn Cotton Exchange Building
in the United States Augusta Cotton Exchange Building, Augusta, Georgia New Orleans Cotton Exchange Building, New Orleans, Louisiana New York Cotton Exchange, New York, New York Cotton-Exchange Building (Oklahoma City, Oklahoma), listed on the National Register of Historic Places (NRHP) Houston Cotton Exchange Building, Houston, Texas Old Cotton Exchange Building, Nacogdoches, Texas, listed on the NRHP
See also Cotton Exchange (disambiguation)