Koželuh (feminine Koželuhová) is a Czech occupational surname meaning 'tanner' (a person who processes animal hides into leather). Notable people with the surname include:
Hana Sládková-Koželuhová (born 1928), Czech tennis player Jan Antonín Koželuh (1738–1814), Czech composer Jan Koželuh (1904–1973), Czech tennis player Josef Koželuh (born 2002), Czech footballer Karel Koželuh (1895–1950), Czech tennis, football, and ice hockey player Mirka Koželuhová (born 1951), Czech tennis player
See also Leopold Koželuch (1747–1818), Czech composer and teacher of classical music