The Pskem Mountain Range (, Pskemskiy Khrebet) or Piskom Mountains, is a mountain range located within the west Tien Shan range of Central Asia, and is a natural border between Kyrgyzstan and Uzbekistan. It extends over from north-east to south-west in the extreme north-eastern finger of Uzbekistan's Tashkent Region. The range is a water divide between the Pskem river to the north and the Chandalash, Chatkal, and Koʻksu rivers to the south.Pskem Range in West Tien Shan mountaineering guide, in Russian. The highest elevations are attained in the north-east of the range: Mount Adelung () and Mount Beshtor ().Big Soviet Encyclopedia, on-line edition, in Russian, accessed June 6, 2011.

The river Pskem flows through the mountains on its way to Lake Charvak.

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