Muddy River may refer to:

Streams Muddy River (Massachusetts), a series of brooks and ponds that runs through sections of Boston's Emerald Necklace Muddy River (Merrymeeting Bay), a river in Maine Muddy River (Nevada), a river in Nevada Muddy River (Sebago Lake), a river in Maine Muddy River (Washington), a river in the state of Washington

Other Muddy River (film), a 1981 Japanese film

See also Brookline, Massachusetts, formerly named Muddy River Muddy Creek (disambiguation) Muddy (disambiguation)