DES or Des may refer to:

Computing Data Encryption Standard, a block cipher that is no longer secure for today's standards DirectShow Editing Services, an Application Programming Interface Discrete event simulation, a kind of scientific modelling

Education Deccan Education Society, a private education institution based in Pune, India. Department of Education and Science (UK), the former name of the Department for Education and Skills , a former degree used in France and French-speaking countries

Medical Diethylstilbestrol, a synthetic estrogen and the origin of the phrase "DES daughter" DES gene, which encodes the desmin protein Diffuse esophageal spasm, a disorder of the esophagus Dissociative Experiences Scale, a questionnaire to screen for dissociative identity disorder Drug-eluting stent, a medical device Dry eye syndrome, also known as keratoconjunctivitis sicca Dysequilibrium syndrome, a congenital disorder of the nervous system

Other uses Dar es Salaam Dark Energy Survey, an astronomy project

Disability Employment Services, a former support program managed by Department of Social Services in Australia Deep Ecliptic Survey, an astronomy project Deep eutectic solvent, an ionic solvent Defence Equipment and Support, British MOD's defence procurement arm Delivered Ex Ship, an international sales term Detached eddy simulation, a model in fluid dynamics Des, a three-part British series about serial killer Dennis Nilsen Desroches Airport, by IATA code Arizona Department of Economic Security, a US government organization providing a variety of social support services to Arizona residents Desmond (name), a male given name in shortened form Desiree (given name), a female given name in shortened form Diethyl sulfate, an organic chemical

See also Desh (disambiguation) Desi (disambiguation) Bachelor of Design (B.Des), an academic degree