Prunella may refer to:
Arts and entertainment Prunella (fairy tale), an Italian fairy tale Prunella, a 1913 play in the United States with Marguerite Clark Prunella (film), a 1918 silent film
Plants and animals Prunella (bird), also known as accentors or dunnocks, a bird genus Prunella (plant), also known as self-heal, a plant genus Prunella (grape), a French wine grape better known as Cinsaut
Other uses Prunella (given name) Prunella (horse), a Thoroughbred racehorse and broodmare Prunella (cloth), an 18th-century worsted fabric Bargnolino, sometimes called prunella, Italian sloe gin