Columbus Historic District may refer to:
in the United States (by state) Columbus Historic District (Columbus, Georgia), listed on the NRHP in Georgia Columbus Historic Riverfront Industrial District, Columbus, Georgia, listed on the NRHP in Georgia Columbus Historic District (Columbus, Indiana), listed on the NRHP in Indiana South Columbus Historic District, Columbus, Mississippi, listed on the NRHP in Mississippi Columbus Downtown Historic District, Columbus, Wisconsin, listed on the NRHP in Wisconsin