Amanda Setton (born December 16, 1985) See also: is an American actress. She is known for her recurring role as Penelope Shafai on The CW's teen drama Gossip Girl (2008–2012), for her role as Kimberly Andrews on the ABC soap opera One Life to Live (2009–2011) and as Brook Lynn Quartermaine on the ABC soap opera General Hospital (2019–present). For the latter role, she received a Daytime Emmy Award nomination for Outstanding Supporting Actress in a Drama Series in 2026. She made her Off-Broadway debut in the comedy play Love, Loss, and What I Wore in late 2011 and was on the first half of season one of the Fox comedy The Mindy Project.
Early life Setton was born in New York City and grew up in Great Neck, where she was vice president of her high school's theater club. She is of Syrian-Jewish ancestry on her father's side and Ashkenazi Jewish on her mother's side. Setton majored in drama at Ithaca College, where she graduated in 2007. In her junior year she studied abroad in Barcelona, Spain in an IES program. Setton completed a comprehensive, two-year Meisner technique program at The Actor's Workshop of Ithaca under the instruction of Eliza VanCort.
Career Setton played Penelope Shafai on the teen drama Gossip Girl from 2008 to 2012. She made her debut on the ABC soap opera One Life to Live as Kimberly Andrews on August 14, 2009. Setton also had small roles in the 2008 films Sex and the City and What Happens in Vegas. The website Daytime Confidential reported on February 21, 2010, that Setton had taped her last episode as Kim on One Life to Live despite being offered a contract and a pay increase.
Setton returned to Gossip Girl in 2010. In April of 2011, she had a heartbreaking role on the 18th episode during the first season of Blue Bloods. It was announced on June 22, 2011, that Setton would be returning to One Life to Live as Kimberly Andrews in August 2011. On July 11, 2012, Setton was cast as a series regular on the Fox comedy series The Mindy Project, playing the role of Shauna Dicanio. However, it was reported on November 20, 2012, that her character would be written out of the show. Setton had a guest role on the pilot episode of the CBS crime drama series Golden Boy, which premiered February 26, 2013, the same day that Setton was cast in the CBS sitcom The Crazy Ones. She portrayed Dr. Mindy Shaw during the fifth season of Hawaii Five-0.
In 2019, she was cast in the role of Brook Lynn Ashton on General Hospital..
Personal life Setton is married, and has three children.
Filmography Film Year Title Role Notes 2005 Surrendering Serendipity: A Rock Opera The God Short film 2008 What Happens in Vegas Hot Woman 2008 Sex and the City Girl Slapping Guy 2008 All the World's a Stage Director's Assistant 2012 Pasolini's Last Words Carlo I / Signora Xxx Documentary film2014That Thing with the CatErica 2015 Black Dog, Red Dog Aazeen 2017That Thing with the Cat!Erica2018Birth of a PoetAazeenShort film
Television Year Claim Role Notes 2008–2012 Gossip Girl Penelope Shafai Recurring role; 31 episodes 2009–2011 One Life to Live Kimberly Andrews Contract: August 14, 2009 – April 2, 2010Recurring: August 22 – December 29, 2011 2010 Mercy Barb 2 episodes (1 uncredited) 2011 Blue Bloods Sylvia Episode: "To Tell the Truth" 2012–2013 Shauna Dicanio Main role (Season 1); 12 episodes 2013 Golden Boy Gemma Bar-Lev Episode: "Pilot" 2013–2014 Lauren Slotsky Main cast; 22 episodes 2014–2015 Hawaii Five-0 Dr. Mindy Shaw Recurring role; 6 episodes 2016 Beauty & the Beast Bootsy Durbrige Episode: "Beast Interrupted" 2019–present General Hospital Brook Lynn Quartermaine Series regular
Awards and nominations + List of awards and nominations Year Award Category Work Result 2026 Daytime Emmy Award Outstanding Supporting Actress in a Drama Series General Hospital
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