Cowart is a surname. Notable people with the surname include:

Byron Cowart (born 1996), American football player Daniel Cowart, man suspected of a plot to assassinate Barack Obama in 2008 Dax Cowart (1947–2019), attorney noted for the ethical issues raised by efforts to sustain his life against his wishes Delma Cowart (1941–2021), American stock car racing driver Donald Cowart (born 1985), American steeplechase runner Gwendolyne Cowart (1920–2003), American pilot during World War II Kaleb Cowart (born 1992), American baseball player Sam Cowart (born 1975), former American football linebacker Shea Cowart, American sprinter

See also A muscadine (Vitis rotundifolia) cultivar