Spears House may refer to:
Spears House (Greenbrier, Arkansas), listed on the NRHP in Arkansas Spears-Craig House, Danville, Kentucky, listed on the NRHP in Kentucky Jacob Spears Distillery, Shawhan, Kentucky, listed on the NRHP in Kentucky Jacob Spears House, Shawhan, Kentucky, listed on the NRHP in Kentucky Spears House (Concord, North Carolina), listed on the NRHP in North Carolina