HFC may stand for:
Businesses and organisations Businesses High Field Consultants, an American atomic imaging company Home Finance Company, Ghana HFC Bank, part of HSBC Finance, United States
Government and military Home Front Command, Israel Hundred Flowers Campaign, China (1956–1957) House Freedom Caucus, in the US House of Representatives
Football clubs Australia Hawthorn Football Club, an Australian-rules club Heidelberg Football Club, an Australian-rules club
England Haughmond F.C. Hendon F.C. Hereford F.C. Histon F.C. Horsham F.C. Hull F.C., a rugby league club Hyde F.C.
Scotland Hanover F.C. (Edinburgh) Heart of Midlothian F.C. ("Hearts") Hibernian F.C.
Elsewhere Hanover F.C., Northern Ireland Heights F.C., Northern Ireland Hyderabad FC, India Hallescher FC, Germany Henan F.C., China Holywood F.C., Northern Ireland Koninklijke HFC, Netherlands
Places Hall for Cornwall, a theatre in Cornwall, England Heng Fa Chuen, Hong Kong, China Heng Fa Chuen station (by MTR station code)
Science and technology Chemicals Hafnium carbide Hydrofluorocarbons
Technologies High frequency content measure, of a signal Hybrid fiber-coaxial, a type of broadband network Hydrogen fuel cell, a type of vehicle power plant