Plymouth Historic District may refer to:
in the United States (by state then city) East Plymouth Historic District, Plymouth, Connecticut, listed on the National Register of Historic Places (NRHP) Plymouth Center Historic District, Plymouth, Connecticut, NRHP-listed Plymouth Downtown Historic District, Plymouth, Indiana, NRHP-listed Plymouth Southside Historic District, Plymouth, Indiana, NRHP-listed Plymouth Village Historic District, Plymouth, Massachusetts, NRHP-listed Plymouth (Columbus, Mississippi), listed on the NRHP in Lowndes County Plymouth Historic District (Plymouth, New Hampshire), NRHP-listed Plymouth Historic District (Plymouth, North Carolina), NRHP-listed Plymouth Historic District (Plymouth, Ohio), listed on the NRHP in Huron County, Ohio, and also in Richland County, Ohio Plymouth Meeting Historic District, Plymouth Meeting, Pennsylvania, NRHP-listed Plymouth Historic District (Plymouth, Vermont), NRHP-listed Downtown Plymouth Historic District in Plymouth, Wisconsin