Mizoguchi (written: 溝口 lit. "gutter/drain entrance") is a Japanese surname. Notable people with the surname include:
Hajime Mizoguchi, musician , Japanese samurai and daimyō Kazuhiro Mizoguchi, javelin thrower Kenji Mizoguchi, filmmaker Koji Mizoguchi (born in 1963), Japanese archaeologist , Japanese daimyō , Japanese daimyō Noriko Mizoguchi, Japanese judoka
Fictional characters Hiroshi Mizoguchi, Hikaru no Go Mizoguchi Makoto, Fighter's History The main character of Yukio Mishima's novel Kinkaku-ji