Holmes House may refer to:
United Kingdom Holmes House, South Duffield, North Yorkshire, England
United States (by state then city) Holmes-Shannon House, Los Angeles, California, listed on the National Register of Historic Places (NRHP) Francis H. Holmes House, New Britain, Connecticut, listed on the NRHP in Hartford County Samuel Holmes House, Highland Park, Illinois, listed on the NRHP in Lake County Perrigo-Holmes House, Boone, Iowa, listed on the NRHP in Boone County Sen. John Holmes House, Alfred, Maine, NRHP-listed Holmes Cottage, Calais, Maine, listed on the NRHP in Washington County Dr. Job Holmes House, Calais, Maine, listed on the NRHP in Washington County Holmes-Crafts Homestead, North Jay, Maine, listed on the NRHP in Franklin County Joseph Holmes House, Cambridge, Massachusetts, NRHP-listed Oliver Wendell Holmes House, Beverly, Massachusetts, NRHP-listed Nels A. Holmes Farmstead, Stambaugh, Michigan, listed on the NRHP in Iron County Holmes House (Magnolia, Mississippi), listed on the NRHP in Pike County William Frederick Holmes House, McComb, Mississippi, listed on the NRHP in Pike County John Holmes House, Cape May Court House, New Jersey, NRHP-listed Holmes–Hendrickson House, Holmdel, New Jersey, listed on the NRHP in Monmouth County Holmes–Tallman House, Monroe Township, New Jersey, listed on the NRHP in Middlesex County Benjamin Holmes House, Salem, New Jersey, NRHP-listed Sedberry-Holmes House, Fayetteville, North Carolina, listed on the NRHP in Cumberland County Gustavus Holmes House, Astoria, Oregon, listed on the NRHP in Clatsop County William L. Holmes House, Oregon City, Oregon, listed on the NRHP in Clackamas County Zack Holmes House, Rapid City, South Dakota, listed on the NRHP in Pennington County
See also Holmes on Homes (TV series) renovation TV show Holmes (disambiguation)