Disseminated coccidioidomycosis is a systemic infection caused by Coccidioides immitis. 15-20% of people with the infection develop skin lesions.

History of treatment In 1959, "Disseminated Coccidioidomycosis Treated with Amphotericin B" was published in the New York State Journal of Medicine, documenting perhaps one of the earliest uses of the drug amphotericin B for a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Disseminated coccidioidomycosis had been lacking specific chemotherapeutic treatment until approximately three years ago when amphotericin B, a polyene antifungal antibiotic, was tried. Since then, there have been a number of reports on the beneficial clinical effect of the drug in patients with coccidioidomycosis.

See also Coccidioidomycosis List of cutaneous conditions

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