Southtown, Southtowns or South Town may refer to:
"Southtown" (song), from the 2000 rap metal album The Fundamental Elements of Southtown by P.O.D. Southtowns, a suburban region in Buffalo, New York SouthtownStar, formerly the Daily Southtown, a newspaper in suburban Chicago South Town, Hampshire, a hamlet in England South Town, setting of Rankin/Bass Animated Entertainment's animated Christmas Special The Year Without a Santa Claus South Town, setting of SNK Playmore's fighting video game series Fatal Fury and Art of Fighting South Town, one of the two municipalities that merged to form Pleasureville, Kentucky Southtown, the near south side of San Antonio, Texas Southtown Center, a shopping center in Bloomington, Minnesota