Quaye is a common Ghanaian surname. Notable people with the surname include:
Abdullah Quaye (born 1980), Ghanaian football midfielder Benjamin W. Quartey Quaye Papafio (1859–1924), physician and politician in the Gold Coast Caleb Quaye (born 1948), English Afro-European rock guitarist and studio musician Daniel Quaye (born 1980), Ghanaian football defender Finley Quaye (born 1974), Scottish musician Ko Quaye (born 1987), Canadian football defensive tackle Lawrence Quaye (born 1984), Ghana born naturalized Qatari footballer Paul Quaye (born 1995), Spanish-born Ghanaian footballer Peter Ofori-Quaye (born 1980), Ghanaian professional association football player Philemon Quaye (1924–2010), Ghanaian soldier, politician, diplomat and religious leader Raphael M. Quaye (born 1975), Liberian basketball player Shamo Quaye (1971–1997), Ghanaian footballer Terri Quaye (born 1940), English singer, pianist, and percussionist