Jonathan Lewis may refer to:
Entertainment Jonathan Guy Lewis (born 1963), English actor Johnny Lewis (1983–2012), American actor Jonathan Lewis (artist) (born 1970), visual artist
Sports Jonathan Lewis (American football) (born 1984), American football player Jonathan Lewis (soccer) (born 1997), American soccer player Jonathan Lewis (motorsport), driver and manager Jon Lewis (cricketer, born 1970), English player and coach
Other Jonathan Lewis (oncologist) (born 1959), oncologist and cancer drug developer Jonathan Lewis (2006–2023), American murder victim Jonathan Lewis (died c. 1820), alleged murderer of Omie Wise
See also Jon Lewis (disambiguation) John Lewis (disambiguation)