Persian astrology, particularly during the Sasanian era and earlier, is considered one of the most important connecting links in the history of global astronomy and astrology. This scientific school was a combination of Babylonian, Indian, and Greek knowledge that developed within the context of Iranian culture. The Sasanian Empire, by establishing scientific centers such as the Academy of Gondishapur, became a hub for the translation and compilation of astronomical and astrological texts. Important texts from Sanskrit and Greek were translated into Middle Persian (Pahlavi). Sasanian astrologers played a fundamental role in developing concepts such as continuous historical astrology and the great conjunction cycles of Jupiter (Ohrmazd) and Saturn (Kewan), which were used to predict major political events and the fates of kingdoms.

Many astrological concepts found in specialized texts today have their roots in Middle Persian and found their way into Latin through Arabic translations, including:

In examining the history of astrology in Iran and the Islamic era, scholars divide this development into three prominent periods:

Sasanian period: During this timeframe, Greek texts were translated into Middle Persian. Figures such as Zadanfarrukh Andarzgar played a key role in this process, and his writings later served as the foundation for astrologers in the Islamic era. Transition of power to the Abbasids: With the rising prominence of Khorasan and the founding of Baghdad, Persian astrologers gained significant political and military influence. Figures such as Mashallah, Abu Ma'shar, and Sahl ibn Bishr served as close advisors to rulers in crucial decision-making and battles. Fundamental achievements: During this era, two major branches were established. The first was "Horary astrology", which was used to find answers to everyday questions by casting a horoscope at that exact moment. The second was "Mundane astrology", in which various national and historical epochs were divided and forecasted based on great conjunctions (the conjunctions of Jupiter and Saturn) and the time of the sun's entry into Aries.

Ancient Persia Astrology was incorporated into the religious and theological framework of Zoroastrianism particularly during the Sasanian period. According to Enrico G. Raffaelli, Zoroastrian priests probably possessed some knowledge of Mesopotamian astral divination and proto-astrology as early as the Achaemenid period, although there is insufficient evidence to determine whether these traditions influenced Zoroastrian theology before Sasanian times. Under the Sasanians, however, astrological doctrines entered the religious corpus itself. The Denkard, for example, presents Shapur I as recovering scientific and astral writings dispersed in India, Byzantium, and other lands. Although Raffaelli does not regard this account as strictly historical, it reflects a broader process through which astrological doctrines of Mesopotamian, Greek, and Indian origin were absorbed into Sasanian intellectual culture and adapted to Zoroastrian thought.

In this Zoroastrian reinterpretation, the celestial realm forms part of the cosmic struggle between good and evil. The Sun, Moon, stars, and zodiacal constellations are classified as beneficial entities, whereas the five planets and the lunar nodes belong to the evil astral forces; the irregular motion of the planets is among the features associated with their negative character. The richest account of these doctrines occurs in the Bundahishn, particularly in its fifth section. The text describes a “horoscope of the world” for the beginning of the period of cosmic mixture, in which several malefic astral bodies occupy positions of exceptional power. The configuration thus represents the initial predominance of evil and helps explain the imperfect and polluted condition of the present world. Although ultimately derived from classical astrology, this world horoscope was substantially reworked in the Zoroastrian tradition, with Raffaelli identifying elements derived from Indian astrological models.

Astrological concepts were also applied to human life and cosmic history. The horoscope of Gayomart, the primordial man, is the only individual birth chart known from Pahlavi literature, and his death at the age of thirty is explained astrologically through the changing positions and strengths of Saturn and Jupiter. The doctrine thereby makes death, regarded in Zoroastrian theology as one of the principal consequences of the assault of evil, part of an astrological scheme. Pahlavi texts also preserve doctrines of millennial chronocratoria, in which zodiacal constellations and especially Saturn exercise rulership over periods of cosmic history, anticipating themes associated with Sasanian historical astrology. In addition, the Anthologies of Zadspram contain a form of astrological melothesia connecting layers and parts of the human body—including marrow, bones, flesh, nerves, veins, skin, and hair—with celestial entities. Raffaelli interprets such doctrines as examples of the creative adaptation of astrological ideas of diverse origins to Zoroastrian cosmology and theology.

One of the distinctive features of the Bundahishn is its combination of traditional Zoroastrian cosmology with later astronomical and astrological learning. D. N. MacKenzie noted that this syncretism is particularly evident in its astrological sections. Fixed stars form part of the celestial forces of Ohrmazd, whereas the wandering planets are portrayed as destructive beings that invade the heavens and contend with the fixed stars. The text assigns individual planetary adversaries to stellar commanders: Mercury is opposed to Sirius, Jupiter to the Great Bear, Mars to Vega, Venus to Sadwēs, and Saturn to the Pole Star, while the Dragon (Gōzihr) and the tailed Muš Parīg are associated with the Sun and Moon.

The Bundahishn also contains what it explicitly calls the "horoscope of the world" (Middle Persian zāyč ī gēhān), representing the celestial configuration at the time of Ahriman's assault upon creation. Its ascendant is given as 19 degrees Cancer; Jupiter is placed in Cancer, Mercury in Virgo, Saturn in Libra, Mars in Capricorn, Venus in Pisces, the Sun in Aries, and the Moon in Taurus, while the Head and Tail of the Dragon occupy Gemini and Sagittarius respectively. MacKenzie's reconstruction of the diagram shows a twelve-house horoscope and demonstrates the extent to which technical astrology had been incorporated into the cosmological narrative of the Bundahishn.

The same text displays familiarity with a substantial body of technical astrological doctrine. It states that each planet in relation to the twelve zodiacal signs possesses its own house, detriment, exaltation, fall, terms, aspects and decans, together with benefic and malefic conditions and other configurations. These passages indicate that the redactors of the Bundahishn had access to a developed system of Hellenistic astrology, although its concepts were reinterpreted within a specifically Zoroastrian cosmological and theological framework.

Antonio Panaino has placed this material within the broader history of Iranian astral knowledge. He argues that the Avestan ritual texts contain no clear references to the five planets, whereas western Iranian communities, owing to their proximity to Mesopotamia, acquired a more developed knowledge of the wandering planets during the first millennium BCE. Four of the planets became associated with major Iranian deities: Jupiter with Ohrmazd, Mars with Wahrām, Venus with Anāhīd, and Mercury with Tīr. Saturn was exceptional, its Iranian name Kēwān being connected instead with a Mesopotamian designation expressing the idea of permanence or steadiness.

According to Panaino, the Zoroastrian demonization of the planets should not simply be derived from Manichaean influence. Rather, it developed through a reformulation of the Zoroastrian concept of the cosmic battle between the forces of Ohrmazd and Ahriman. Fixed stars were regarded as orderly divine protectors of the heavens, whereas the planets, with their apparently irregular motions, stations and retrogradations, could be interpreted as agents of disorder. Their astronomical behaviour thus acquired a moral and theological meaning within the Zoroastrian cosmological system. Panaino considers it more likely that this process began during the Seleucid and early Parthian periods, when Hellenistic astrology was becoming established in Iranian lands, rather than being a specifically Sasanian borrowing from Manichaeism.

This theological classification also created a tension with practical astrology. In conventional astrology Jupiter and Venus were benefic, Saturn and Mars malefic, while Mercury could assume either quality according to its configurations. Zoroastrian dualism, however, made such internal differentiation problematic: celestial beings were expected to belong either to the forces of order or to those of disorder. Consequently, the wandering planets as a class were assigned to the demonic side of the cosmic conflict, even though practical astrological doctrine continued to distinguish between benefic and malefic planets.

Characteristics Persian astrology may be understood as a group of astrological traditions that developed within the Iranian cultural sphere, particularly during the Sasanian period and the early Islamic centuries. These traditions combined Iranian material with elements derived from Babylonian, Greek, and Indian astronomy and astrology, some of which were subsequently transmitted through Arabic-language scholarship to other parts of the Islamic world and medieval Europe.

Iranian astrologer and researcher Ehsan Khazeni describes Persian astrology as an extensive tradition with approximately fifteen centuries of historical continuity and associates it with the wider cultural geography of Greater Iran. Astronomy, mathematical geography, and astrology were historically important disciplines within this region. Before the International Meridian Conference of 1884, however, there was no single universally accepted prime meridian; different astronomical and geographical traditions used different reference meridians. The 1884 conference adopted the Greenwich meridian as the international reference meridian.

In the Persian astrology, considerable emphasis is placed on the calculation and quantitative assessment of planetary conditions. These include exaltation, fall, and other forms of planetary dignity and debility. Khazeni describes a system involving 157 conditions or factors used in evaluating planetary strength and weakness. Here, “quantitative” refers to the internal computational procedures of the astrological tradition rather than to empirical scientific validation of astrological prediction.

Persian astrology is also closely connected with other intellectual traditions, including Iranian mythology and cosmology as represented in the Bundahishn, Illuminationist and Peripatetic philosophy, Hermeticism, mathematical geography, calendrical studies, and spherical astronomy. Such connections have a long historical background: during the Sasanian period, Greek and Sanskrit astronomical and astrological works were translated into Middle Persian, and portions of this material were subsequently incorporated into astronomy and astrology of the Islamic period.

Techniques and instrumentsو important within the Persian traditionو include the astrolabe, quantitative systems of planetary dignity and debility, time-lord techniques such as Firdaria, the interpretation of the great conjunctions of Saturn and Jupiter, the 28 lunar mansions, various forms of electional astrology, and the determination of the possible positions or candidates for the Hyleg. Horoscopic houses, lunar mansions, and related techniques are also attested in surviving Iranian and Islamic astrological texts.