Farlowella mariaelenae is a species of freshwater ray-finned fish belonging to the family Loricariidae, the suckermouth armored catfishes, and the subfamily Loricariinae, the mailed catfishes. This catfish is found in Colombia and Venezuela. This species reaches a standard length of .

The specific name honors Felipe J. Martín Salazar's "great companion", his wife María Elena.

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