Bootsie or Bootsy may refer to:

Bootsie Barnes, tenor saxophonist from Philadelphia, PA Bootsie and Snudge, a UK television sitcom series from the 1960s Bootsie, the name of the character "Roadrunner" () in the English subtitles of the film Kontroll Bootsie Neal, former politician in Dayton, Ohio Bootsie (later "Brutus"), the original name of Polly's cat in "The Cat Who..." series Bootsie Snootie, a character from the show "PB&J Otter", and Ootsie’s twin sister. Bootsy Collins (born 1951), funk bassist, singer, and songwriter Bootsy Thornton, an American former baseball player Caligula, third Emperor of Rome, who was given the name in his youth, which translates roughly to “Bootsie” or “Little Boots”.