22nd U-boat Flotilla ("22. Unterseebootsflottille") was formed in January 1941 in Gotenhafen under the command of Korvettenkapitän Wilhelm Ambrosius. The flotilla was disbanded in May 1945.
Flotilla commanders DurationCommander January 1941 – January 1944 Korvettenkapitän Wilhelm Ambrosius January 1944 – July 1944 Korvettenkapitän Wolfgang Lüth July 1944 – May 1945 Korvettenkapitän Heinrich Bleichrodt
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