McGrail is a surname. Notable people with the surname include:
Ben McGrail (contemporary), British broadcast journalist Edwina McGrail (born 1950), Welsh artist and poet Joe McGrail (born 1964), American gridiron football player John McGrail (born 1956), American long-distance runner Nuala Anne McGrail, a protagonist in the Nuala Anne McGrail series of mystery novels by Father Andrew M. Greeley Peter McGrail (born 1996), British boxer Stephen McGrail (born 1948), American politician from Massachusetts Walter McGrail (1888–1970), American film actor