Sambrook or Sambrooke may refer to:
Places Sambrook, Shropshire, a village in England
People with the surname Andrew Sambrook (born 1979), English footballer Clare Sambrook, English freelance journalist and author Gary Sambrook, Conservative MP for Birmingham Northfield since 2019 Joseph Sambrook (born 1939), British molecular biologist Richard Sambrook, Vice Chairman and Chief Content Officer of the Edelman public relations agency
Other uses Sambrooke Freeman (c. 1721 – 1782), member of the Freeman family of Fawley Court near Henley-on-Thames, England Sambrook's Brewery, a brewery in Battersea, London