Commerce Building may refer to:
Commerce Building (St. Paul, Minnesota), listed on the NRHP in Minnesota Commerce Building (Everett, Washington), listed on the NRHP in Washington Commerce Building, Washington, D.C., the Herbert C. Hoover Building, site of the National Aquarium Commerce Building/Hancock Building, Miami, Oklahoma, National Register of Historic Places listings in Ottawa County, Oklahoma Commerce Building, the former headquarters of the Port Authority of New York and New Jerser, formerly known as Union Inland Terminal #1 and now as 111 Eighth Avenue
See also Chamber of Commerce Building (disambiguation)