Rhyme & Reason may refer to:
Film and television Rhyme & Reason (film), a 1997 documentary film about rap and hip hop Rhyme and Reason (game show), a 1975–1976 American game show
Music Rhyme & Reason (Missing Persons album), 1984 Rhyme & Reason (Ted Nash album), 1999 Rhyme & Reason (soundtrack), from the 1997 film A Rhyme & Reason, an EP by Against All Will, 2009 "Rhyme and Reason", a song by the Cat Empire from The Sun, 2002 "Rhyme & Reason", a song by Dave Matthews Band from Under the Table and Dreaming, 1994
See also "Rhyme nor reason", a phrase originated by Edmund Spenser "Rhyme or Reason", a 2013 song by Eminem Rhyme-as-reason effect, a cognitive bias