Catherine Blake (1762–1831) was the wife and assistant of William Blake.

Catherine Blake or similar may also refer to: People Catherine C. Blake (1950–2026), United States federal judge Katherine Blake (actress) (1921–1991), South African-born British actress Katharine Blake (singer) (born 1970), British musician Dorothy J. Heydt (1942–2022), American author, pen name Katherine Blake Katherine Devereux Blake (1858–1950), American educator, peace and women's rights activist Catherine Blake (née Wright), mother of William Blake

Fictional entities Katherine Blake (character), killer on the soap opera Shortland Street

See also Katarina Eriksdotter (12th-century), Swedish princess, married to Nils Blake Kathy Blake (Kathleen Blake, born 1946), American tennis player