José Diego may refer to:
Diego José de Cádiz (1743–1801), a Spanish Capuchin friar and preacher from the Andalusia region. José de Diego (1866–1918), a Puerto Rican statesman, journalist, poet, lawyer, and advocate for independence. José Tormos Diego (1890–1977), a Puerto Rican politician who served as mayor of Ponce. José Diego (footballer), (born 1954), a Spanish former footballer who played as a midfielder for Real Sociedad and the Spain national team.
See also Diego José, Argentine professional footballer. Diego José Abad, Jesuit poet and translator in New Spain and Italy.