Mirifica may refer to:

Biology Capparis mirifica is a species of plant in the family Capparaceae. Melibe mirifica is a species of sea slug, a marine gastropod mollusk in the family Tethydidae. Lewinia mirifica is a species of bird in the family Rallidae. Pueraria mirifica is a plant found in northern and north eastern Thailand and Myanmar.

Religion Inter Mirifica is the Second Vatican Council's Decree on the Media of Social Communications.