Independence Historic District may refer to:
Independence Historic District (Evansville, Indiana), listed on the NRHP in Indiana Independence Downtown Historic District, Independence, KS, listed on the NRHP in Kansas Independence Historic District (Independence, Louisiana), listed on the NRHP in Louisiana Independence Historic District (Independence, Oregon), listed on the NRHP in Oregon Independence Heights Residential Historic District, Houston, TX, listed on the NRHP in Texas