HDU may refer to:
Hangzhou Dianzi University, in Hangzhou, China Hard disk drive Hồng Đức University, in Vietnam High dependency unit, a hospital facility High Dependency Unit (band), a New Zealand psychedelic rock band High dependency unit (mental health), a psychiatric treatment facility Croatian Phonographic Association (HDU, Hrvatska diskografska udruga) that publishes the Croatian music chart Top of the Shops