Luer (also Lüer) is a Germanic surname. It may refer to:
Carlyle A. Luer (1922–2019), American botanist specializing in orchids Greg Luer (born 1994), English footballer Hermann Wülfing Luer (?–1883), German instrument maker; inventor of the Luer taper Hugo Gunckel Lüer (1901–1997), Chilean pharmacist, botanist, and university professor Karl-Hermann Lüer (1933–2014), German saxophonist and flautist Ludwig Luer ( WWI-era), German flying ace
See also Luer taper, a system for making leak-free connections between pieces of medical or laboratory equipment Luers, people with this surname